Course topics: • The course contents: • Introduction, basic terms and concepts • Cell division - mitosis, meiosis • Basic principles of heredity • Monogene diseases - characteristics and occurrence, autosoma recessive and dominant hereditary diseases, recessive diseases linked to x- chromosome - inheritance criteria, examples • Molecular genetics - DNA structure, transcription, translation, genetic code, human genome • Mutations - spontaneous, induced • Biochemical genetics and pharmacogenetics • Multifactorial diseases - characteristics, incidence, estimation of genetic risk, twins, empirical, relative and odds risk, examples • Cytogenetics - chromosome aberrations, occurrence and their clinical manifestations, most common cases of euploidy, aneuploidy and structural aberrations in humans • Mitochondrial genetic diseases - characteristics, mt-DNA, examples • Oncogenetics - genetic determination of malignity, examples • Population genetics - basic principles and mathematical relations, genetic epidemiology • Genetic prevention - primary, secondary, tertiary • Ethical and legal problems of medical genetics
Information sheetSupervisors and educators:
doc. PhDr. Silvia Puteková, PhD. - Kogarant
doc. PhDr. Róbert Ochaba, PhD. - Zabezpečuje, Hlavný garant
doc. RNDr. Soňa Kucharíková, PhD. - Zabezpečuje, Skúšajúci, Kogarant, Zodpovedný za elearning, Vedúci semináru, Prednášajúci
PhDr. Michal Rafajdus, PhD. - Kogarant
doc. Ing. Margaréta Kačmariková, PhD. - Kogarant
PhDr. Jarmila Pekarčíková, PhD. - Kogarant
Code: VZB06
Period: ZS
Credits: 3
- Pedagóg: Soňa Kucharíková